In addition, the IC receives inputs from the auditory cortex, the medial division of the medial geniculate body, the posterior limitans, suprapeduncular nucleus and subparafascicular intralaminar nuclei of the thalamus, the substantia nigra pars compacta lateralis, the dorsolateral periaqueductal gray, the nucleus of the brachium of the inferior colliculus (or inferior brachium) and deep layers of the superior colliculus. It has been shown that great majority of auditory fibers ascending in the lateral lemniscus terminate in the CNIC. All nuclei except the contralateral ventral nucleus of the lateral lemniscus send projections to the central nucleus (CNIC) bilaterally. The input connections to the inferior colliculus are composed of many brainstem nuclei. Of the three subdivisions the central nucleus of IC (CNIC) is the principal way station for ascending auditory information in the IC. IC are large auditory nuclei on the right and left sides of the midbrain. Sound location data thus becomes fully integrated by the inferior colliculus. The inferior colliculus is the first place where vertically orienting data from the fusiform cells in the dorsal cochlear nucleus can finally synapse with horizontally orienting data. The inferior colliculi of the midbrain are located just below the visual processing centers known as the superior colliculi. The inferior colliculus has three subdivisions – the central nucleus, the dorsal cortex by which it is surrounded, and an external cortex which is located laterally. The inferior colliculus lies caudal to its counterpart – the superior colliculus – above the trochlear nerve, and at the base of the projection of the medial geniculate nucleus and the lateral geniculate nucleus. The inferior colliculi together with the superior colliculi form the eminences of the corpora quadrigemina, and also part of the tectal region of the midbrain. This multisensory integration may underlie a filtering of self-effected sounds from vocalization, chewing, or respiration activities. Its bimodal neurons are implicated in auditory- somatosensory interaction, receiving projections from somatosensory nuclei. The inferior colliculus has three subdivisions: the central nucleus, a dorsal cortex by which it is surrounded, and an external cortex which is located laterally. The inferior colliculus ( IC) ( Latin for lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex.
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